A template-proximal RNA paired element contributes to Saccharomyces cerevisiae telomerase activity.

@article{Seto2003ATR,
  title={A template-proximal RNA paired element contributes to Saccharomyces cerevisiae telomerase activity.},
  author={Anita G Seto and Kfir Baruch Umansky and Yehuda Tzfati and Arthur J. Zaug and Elizabeth H Blackburn and Thomas R Cech},
  journal={RNA},
  year={2003},
  volume={9 11},
  pages={1323-32}
}
The ribonucleoprotein complex telomerase is critical for replenishing chromosome-end sequence during eukaryotic DNA replication. The template for the addition of telomeric repeats is provided by the RNA component of telomerase. However, in budding yeast, little is known about the structure and function of most of the remainder of the telomerase RNA. Here, we report the identification of a paired element located immediately 5' of the template region in the Saccharomyces cerevisiae telomerase RNA… CONTINUE READING
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