A temperature-sensitive cell-cycle mutant of mammalian cells, tsJT16, is defective in a function operating soon after growth stimulation.

Abstract

A temperature-sensitive cell-cycle mutant, tsJT16, which has been isolated from Fischer rat fibroblasts, was defective in the function(s) that operated soon after growth stimulation. When G0-arrested tsJT16 was stimulated to proliferate, it entered the S phase after 12-15 h at 34 degrees C but failed to do so at 40 degrees C. The function mutated in tsJT16… (More)

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@article{Takasuka1990ATC, title={A temperature-sensitive cell-cycle mutant of mammalian cells, tsJT16, is defective in a function operating soon after growth stimulation.}, author={Taichi E. Takasuka and Jun Ninomiya-Tsuji and M Sakayama and S. Ishibashi and Tomomi Ide}, journal={Cell structure and function}, year={1990}, volume={15 1}, pages={39-45} }