A temperature-regulated Campylobacter jejuni gluconate dehydrogenase is involved in respiration-dependent energy conservation and chicken colonization.

@article{Pajaniappan2008ATC,
  title={A temperature-regulated Campylobacter jejuni gluconate dehydrogenase is involved in respiration-dependent energy conservation and chicken colonization.},
  author={Mohanasundari Pajaniappan and Johanna E Hall and Shaun A. Cawthraw and D G Newell and Erin C. Gaynor and Joshua Alan Fields and Kimberly M. Rathbun and Willie Andrew Agee and Christopher M. Burns and Stephen John Hall and David A Kelly and Stuart A Thompson},
  journal={Molecular microbiology},
  year={2008},
  volume={68 2},
  pages={
          474-91
        }
}
Campylobacter jejuni is a gastrointestinal pathogen of humans but can asymptomatically colonize the avian gut. C. jejuni therefore grows at both 37 degrees C and 42 degrees C, the internal temperatures of humans and birds respectively. Microarray and proteomic studies on temperature regulation in C. jejuni strain 81-176 revealed the upregulation at 42 degrees C of two proteins, Cj0414 and Cj0415, orthologous to gluconate dehydrogenase (GADH) from Pectobacterium cypripedii. 81-176 demonstrated… CONTINUE READING
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