A technique of bone marrow collection from vertebral bodies of cynomolgus macaques for transplant studies.

@article{Flores2005ATO,
  title={A technique of bone marrow collection from vertebral bodies of cynomolgus macaques for transplant studies.},
  author={M. Gonzalez Flores and Bari Holm and Michael J. Larson and Macy K Lau and Ming-Sing Si and Robert J Lowsky and G{\'e}raldine Rousvoal and F. Carl Grumet and Samuel Strober and Richard Hoppe and Bruce A. Reitz and Dominic C. Borie},
  journal={The Journal of surgical research},
  year={2005},
  volume={124 2},
  pages={280-8}
}
BACKGROUND Strategies to induce donor-specific allograft tolerance are best tested in preclinical models developed in nonhuman primates (NHPs). Most protocols prepare the recipient by infusing hematopoietic cells from the donor. We report here a procedure to isolate and characterize large numbers of bone marrow cells (BMCs) from cynomolgus monkeys (cynos) that can then successfully be transplanted into conditioned recipients. MATERIALS AND METHODS Vertebral columns of five cynos were excised… CONTINUE READING