A technique for controlled sensory denervation of the rabbit cornea

  title={A technique for controlled sensory denervation of the rabbit cornea},
  author={Bernd Schimmelpfennig and Roger Beuerman},
  journal={Graefe's Archive for Clinical and Experimental Ophthalmology},
Complications arising from the procedure to produce denervation of the cornea have made experiments on the trophic role of trigeminal nerve difficult. In this study, controlled lesions of the rabbit trigeminal ganglion were produced by radio-frequency thermocoagulation, delivered by a needle electrode inserted through the soft palate of the mouth. The advantages of the procedure were low mortality (<5%), permanent destruction of sensory neurons, and absence of spurious ocular effects. Two… CONTINUE READING


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