A tasty morsel: the role of the dorsal vagal complex in the regulation of food intake and swallowing. Focus on "BDNF/TrkB signaling interacts with GABAergic system to inhibit rhythmic swallowing in the rat," by Bariohay et al.

@article{Bailey2008ATM,
  title={A tasty morsel: the role of the dorsal vagal complex in the regulation of food intake and swallowing. Focus on "BDNF/TrkB signaling interacts with GABAergic system to inhibit rhythmic swallowing in the rat," by Bariohay et al.},
  author={E. Fiona Bailey},
  journal={American journal of physiology. Regulatory, integrative and comparative physiology},
  year={2008},
  volume={295 4},
  pages={
          R1048-9
        }
}
  • E. F. Bailey
  • Published 1 October 2008
  • Biology
  • American journal of physiology. Regulatory, integrative and comparative physiology
energy balance depends on the regulation of two central circuits that control feeding behavior. On one hand, the central nervous system (CNS) must coordinate and integrate appetite, food-seeking behavior, and thermoregulation. On the other hand, signals relating to satiety (e.g., from the gut) and 
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The role of gut hormones and the hypothalamus in appetite regulation.
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The current understanding of the role of gut hormones and the hypothalamus on food intake and body weight control is reviewed to offer the opportunity to develop successful treatments for obesity.
Brainstem Control of Deglutition: Swallowing Pattern Generator
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Recent data indicate that the CPG may show some degree of flexibility, with neurons participating to the activity of other brainstem CPGs, providing interesting neuroplasticity capabilities.
Neuroendocrine control of metabolism
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Knowledge about all components of this neuroendocrine circuit will be helpful in developing novel therapeutic approaches against the metabolic syndrome and its components.
Effects of GLP-1 on appetite and body weight : focus on the central nervous system Chapter 2
TLDR
This review summarises the evidence for a physiological role of GLP-1 in the central regulation of feeding behaviour and the different routes of action involved and provides an overview of presently available data on pharmacological stimulation of GLPs leading to alterations in CNS activity, reductions in food intake and weight loss.
Effects of glucagon-like peptide 1 on appetite and body weight: focus on the CNS.
TLDR
This review summarises the evidence for a physiological role of GLP-1 in the central regulation of feeding behaviour and the different routes of action involved, and provides an overview of presently available data on pharmacological stimulation of GLPs leading to alterations in CNS activity, reductions in food intake and weight loss.
Effects of glucagon-like peptide 1 on appetite and body weight: focus on the CNS
TLDR
This review summarises the evidence for a physiological role of GLP-1 in the central regulation of feeding behaviour and the different routes of action involved, and provides an overview of presently available data on pharmacological stimulation of GLPs leading to alterations in CNS activity, reductions in food intake and weight loss.
Obesity and Appetite Control
TLDR
The role of gut hormones and their related neuronal networks (the gut-brain axis) in appetite control, and their potentials as novel therapies for obesity are focused on.
The Gut Hormones in Appetite Regulation
TLDR
The role of gut hormones in the regulation of food intake and body weight is discussed and several gut hormones have been implicated.
TRPV1-dependent regulation of synaptic activity in the mouse dorsal motor nucleus of the vagus nerve
TLDR
The data demonstrate that at physiological range of temperature TRPV1 contributes to presynaptic neurotransmission of DMV neurons.
Gut Hormones and Appetite Control: A Focus on PYY and GLP-1 as Therapeutic Targets in Obesity
TLDR
An overview of the central control of food intake and the role of PYY and GLP-1 in appetite control is provided and key translational animal and human studies are reviewed.
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References

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Results reviewed are consistent with a distributionist model for the control of energy balance that emphasizes: (i) control mechanisms endemic to hypothalamus and brainstem that drive their unique effector systems on the basis of local interoceptive, and (ii) a set of uni- and bidirectional interactions that coordinate adaptive neuroendocrine, autonomic, and behavioral responses to changes in metabolic status.
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TLDR
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