A target-dose finding study of clozapine in patients with schizophrenia.

@article{Bennett1996ATF,
  title={A target-dose finding study of clozapine in patients with schizophrenia.},
  author={Jerry A. Bennett and Paul E. Keck},
  journal={Annals of clinical psychiatry : official journal of the American Academy of Clinical Psychiatrists},
  year={1996},
  volume={8 1},
  pages={19-21}
}
Evidence from recent studies suggests that clozapine plasma concentrations greater than 350 ng/ml are correlated with therapeutic response. However, little is known about the clozapine dosages required to achieve these plasma concentrations. The purpose of this study was to determine if a target dose of 6 mg/kg/day of clozapine would produce a steady state… CONTINUE READING