A tandem repeat of MUC1 core protein induces a weak in vitro immune response in human B cells

Abstract

We have recently described an efficient method to study the human humoral immune response in vitro and to generate isotype-switched, antigen-specific human B cells, which has allowed us to produce high-affinity IgG antibodies against different peptides. In an attempt to study the in vitro immune response against self-antigens, such as tumour-associated… (More)
DOI: 10.1007/s002620050528

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