A tagging SNP in INSIG2 is associated with obesity-related phenotypes among Samoans

@inproceedings{Deka2009ATS,
  title={A tagging SNP in INSIG2 is associated with obesity-related phenotypes among Samoans},
  author={Ranjan Deka and Ling Fei Xu and Prodipto Pal and Palanitina T Toelupe and Tuiasina Salamo Laumoli and Huifeng Xi and Ge Zhang and Daniel E. Weeks and S T McGarvey},
  booktitle={BMC Medical Genetics},
  year={2009}
}
A genome wide association study found significant association of a sequence variant, rs7566605, in the insulin-induced gene 2 (INSIG2) with obesity. However, the association remained inconclusive in follow-up studies. We tested for association of four tagging SNPs (tagSNPs) including this variant with body mass index (BMI) and abdominal circumference (ABDCIR) in the Samoans of the Western Pacific, a population with high levels of obesity. We studied 907 adult Samoan participants from a… CONTINUE READING
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Portability of the HapMap: linkage disequilibrium sharing between the continental populations and the Samoans of Polynesia

  • R Deka, W Huang, +6 authors L Jin
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