A systematic search method for the identification of tightly packed transmembrane parallel alpha-helices.

@article{Akula2005ASS,
  title={A systematic search method for the identification of tightly packed transmembrane parallel alpha-helices.},
  author={Nagaraju Akula and Nagarajan Pattabiraman},
  journal={Journal of biomolecular structure & dynamics},
  year={2005},
  volume={22 6},
  pages={625-34}
}
Membrane proteins play a major role in number of biological processes such as signaling pathways. The determination of the three-dimensional structure of these proteins is increasingly important for our understanding of their structure-function relationships. Due to the difficulty in isolating membrane proteins for X-ray diffraction studies, computational techniques are being developed to generate the 3D structures of TM domains. Here, we present a systematic search method for the… CONTINUE READING

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