A systematic review of viral infections associated with oral involvement in cancer patients: a spotlight on Herpesviridea

@article{Elad2010ASR,
  title={A systematic review of viral infections associated with oral involvement in cancer patients: a spotlight on Herpesviridea},
  author={Sharon Elad and Yehuda Zadik and Ian Hewson and Allan J Hovan and Maria Elvira Pizzigatti Corr{\^e}a and Richard M Logan and Linda S. Elting and Fred K. L. Spijkervet and Michael T. Brennan and Oral Care Study Group Multinational Association of Supp Viral Infections Section},
  journal={Supportive Care in Cancer},
  year={2010},
  volume={18},
  pages={993-1006}
}
PurposeOur aim was to evaluate the literature for the prevalence of and interventions for oral viral infections and, based on scientific evidence, point to effective treatment protocols. Quality of life (QOL) and economic impact were assessed if available in the articles reviewed.MethodsOur search of the English literature focused on oral viral infections in cancer patients within the timeframe of 1989–2007. Review methods were standardized. Cohort studies were used to determine the weighted… 
A systematic review of oral herpetic viral infections in cancer patients: commonly used outcome measures and interventions
TLDR
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Investigation of the oral infections and manifestations seen in patients with advanced cancer
TLDR
Oral infection is prevalent among advanced cancer patients and associated with therapy methods and risk factors, and more oral health care should be carried out for the patients with advanced malignant tumor.
Prospective evaluation of HSV, Candida spp., and oral bacteria on the severity of oral mucositis in pediatric acute lymphoblastic leukemia
BackgroundOral mucositis is a common collateral effect among the secondary complications resulting from chemotherapy. The objective of this study was to prospectively evaluate the association of
Seroprevalence of herpes virus associated with the presence and severity of oral mucositis in children diagnosed with acute lymphoid leukemia.
TLDR
It was possible to conclude that infection by the herpes viruses HSV-1, EBV, and CMV is ubiquitous in the studied population and that HSv-1 may be a risk factor for aggravating the severity of mucositis.
Seroprevalence of HSV-1/2 and correlation with aggravation of oral mucositis in patients with squamous cell carcinoma of the head and neck region submitted to antineoplastic treatment
TLDR
The reactivation of HSV-1/2 was shown to be relatively infrequent and there was no correlation between presence of the virus and aggravation of oral mucositis resulting from antineoplastic treatment.
PREVALENCE OF HERPESVIRUSES IN PATIENTS WITH LARYNX AND HYPOPHARYNX SQUAMOUS CELL CARCINOMA
TLDR
There was no statistically significant correlation between the presence of EBV, CMV, HSV-1 and G and epidemiological features such as place of residence and T and alcohol use.
Herpesvirus in the oral cavity of children with leukaemia and its impact on the oral bacterial community profile
TLDR
The prevalence of herpesviruses and the qualitative bacterial profiles was higher in children with leukaemia and HCMV,HHV-7 and HHV-8 were related to the use of chemotherapy.
HSV-1 as well as HSV-2 is frequent in oral mucosal lesions of children on chemotherapy
TLDR
In a novel finding, real-time PCR detected copies of HSV-2 in 69 % cases, all missed by conventional PCR, which is commonly shed from oral mucosal lesions in children receiving chemotherapy.
TNF as marker of oral candidiasis, HSV infection, and mucositis onset during chemotherapy in leukemia patients.
TLDR
AL patients undergoing chemotherapy with high salivary TNF levels were more likely to develop HSV infection, OC, and OM.
Viral loads and antiviral resistance of herpesviruses and oral ulcerations in hematopoietic stem cell transplant recipients
TLDR
HSV-1 is a predictor of ulcerations on non-keratinized as well as keratinized oral mucosa following HSCT, and the role of EBV deserves further study.
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Abstract The successful prevention and management of oral infections and infections from the oral cavity in cancer patients are based on identification of risk patients, selection of patients for
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