A systematic review of treatments for mild traumatic brain injury

@article{Comper2005ASR,
  title={A systematic review of treatments for mild traumatic brain injury},
  author={Paul Comper and Sean M. Bisschop and Nancy Carnide and Andrea C. Tricco},
  journal={Brain Injury},
  year={2005},
  volume={19},
  pages={863 - 880}
}
OBJECTIVES To assess the effectiveness of interventions for mild traumatic brain injury (MTBI) in adults as found in the literature. [] Key MethodRESEARCH DESIGN Systematic review of the literature. METHODS Six electronic databases and 18 journals within the brain injury field were manually searched between the years 1980-2003. References from articles were scanned for further literature. Studies that met broad inclusion criteria were subjected to a formal test of relevance.
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229 Citations
Highly Influential Citations
13
Background Citations
62
Methods Citations
5
Results Citations
6

229 Citations

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Citation Type

Treatment outcomes in mild traumatic brain injury: a systematic review of randomized controlled trials
TLDR
Traditional education and reassurance can no longer be recommended as having the best evidence base for efficacy as compared to psychological and rehabilitative approaches, and guidelines should begin to reflect this.
Perceptions of mild traumatic brain injury in adults: a scoping review
TLDR
Perceptions of mild traumatic brain injury (mTBI) and recovery have been associated with health outcomes and are worth considering in clinical rehabilitation practice, and potential implications for the rehabilitation process are discussed.
Interventions provided in the acute phase for mild traumatic brain injury: a systematic review
TLDR
There is a paucity of well-designed clinical studies for patients who sustain mTBI, and the large variability in outcomes measured in studies limits comparison between them.
Overview of pharmacological interventions after traumatic brain injuries: impact on selected outcomes
TLDR
A need for adequately powered and rigorous randomized clinical trials (RCTs) to provide generalizable evidence on the effectiveness of pharmacologic interventions for TBI is demonstrated.
A systematic review of psychological treatments for mild traumatic brain injury: An update on the evidence
TLDR
Although the methodological quality remains poor, mild supportive evidence was found for educational interventions provided early following injury, however, the routine provision of interventions for all MTBI cases may not be effective.
A systematic literature review of psychotherapeutic treatment of prolonged symptoms after mild traumatic brain injury
TLDR
A systematic review of the literature on psychotherapeutic interventions specifically for patients with prolonged symptoms (> 3 months after injury) after mTBI revealed several methodological limitations in the included studies, leading to the conclusion that it is premature to make any strong recommendations on psychtherapeutic treatment of prolonged symptoms aftermTBI.
Pharmacological interventions in traumatic brain injury: Can we rely on systematic reviews for evidence?
Association of Pharmacological Interventions With Symptom Burden Reduction in Patients With Mild Traumatic Brain Injury: A Systematic Review.
TLDR
A limited number of high-quality, clinically meaningful studies are found, particularly among children and individuals in the acute stage of injury; therefore, performing an evidence-based analysis that would inform clinical decision-making was not possible.
Family involvement in behaviour management following acquired brain injury (ABI) in community settings: A systematic review
TLDR
There is limited research and lack of high evidence studies evaluating family involvement in behaviour management following ABI; therefore, no conclusions can be drawn regarding its efficacy.
A brief review of traumatic brain injury rehabilitation.
TLDR
There is promising evidence of improved outcome and functional benefits with early induction into a transdisciplinary brain injury rehabilitation programme, however, TBI research is fraught with difficulties because of an intrinsically heterogeneous population due to age, injury severity and type, functional outcome measures and small samples.
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References

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Effect of cognitive rehabilitation on outcomes for persons with traumatic brain injury: A systematic review.
TLDR
Two randomized controlled trials and one observational study provided evidence that specific forms of cognitive rehabilitation reduce memory failures and anxiety, and improve self-concept and interpersonal relationships for persons with TBI.
A randomized trial of two treatments for mild traumatic brain injury.
TLDR
Brief educational intervention given soon after MTBI appears to be adequate for most MTBI survivors and did not differ from each other on any symptom-related, functional, or vocational variables 3-4 months after their baseline session.
Homeopathic treatment of mild traumatic brain injury: A randomized, double-blind, placebo-controlled clinical trial.
TLDR
This study suggests that homeopathy may have a role in treating persistent MTBI, and indicates a significant improvement from the homeopathic treatment versus the control and translate into clinically significant outcomes.
Impact of early intervention on outcome following mild head injury in adults
TLDR
Patients in the intervention group who were seen at one week and given the information booklet reported fewer symptoms overall and were significantly less stressed at three months after the injury.
Minor traumatic brain injury: review of clinical data and appropriate evaluation and treatment.
TLDR
Various aspects of the etiology of MTBI are described, with recommended evaluation and treatment guidelines, and a functional assessment scale specifically for persons with MTBI is presented.
A randomized trial of two treatments for mild traumatic brain injury: 1 year follow-up.
TLDR
Brief educational intervention given soon after MTBI appears to be as helpful as more intensive treatment for most MTBI survivors for at least 12 months post-injury.
Neuropsychological rehabilitation of mild traumatic brain injury.
TLDR
A retrospective analysis of the results of a neuropsychological rehabilitation programme for 20 patients with MTBI found that there may be significant variability in recovery and response to treatment after MTBI.
Clinicopathological heterogeneity in the classification of mild head injury.
TLDR
The need for more precise research diagnostic criteria in the study of neurobehavioral outcome after mild head injury is demonstrated and the implicit assumption of clinicopathological homogeneity among patients with GCS scores of 13 to 15 is challenged.
Mild head injury classification.
TLDR
Analysis of the various complications of mild CHI revealed that the presence of an intracranial lesion was related to more severe neurobehavioral sequelae than injuries complicated by a depressed fracture.
Remediation of 'working attention' in mild traumatic brain injury
TLDR
Preliminary results concerning the effectiveness of an intervention for attentional deficits after mild traumatic brain injury suggest that the principal effect of the intervention was on working memory, i.e. the ability to temporarily maintain and manipulate information during task performance, with no direct effect on processing speed.
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