A systematic review of the safety and effectiveness of repetitive transcranial magnetic stimulation in the treatment of peripartum depression.

@article{Cole2019ASR,
  title={A systematic review of the safety and effectiveness of repetitive transcranial magnetic stimulation in the treatment of peripartum depression.},
  author={Jaeden Cole and Katherine Stuart Bright and Lisa Gagnon and Alexander McGirr},
  journal={Journal of psychiatric research},
  year={2019},
  volume={115},
  pages={
          142-150
        }
}
Repetitive transcranial magnetic stimulation treatment for peripartum depression: systematic review & meta-analysis
TLDR
In conclusion, repetitive transcranial magnetic stimulation can be considered an alternative treatment to treat peripartum depression to avoid exposure of fetuses to drugs and the severe side effects of electroconvulsive therapy.
Treatment Repetitive Transcranial Magnetic Stimulation to Peripartum Depression: Systematic Review
TLDR
rTMS might be an attractive alternative treatment for pregnant women who are afraid of chemical effect to their child and life threatening side effect of ECT and could reduce socioeconomic costs of peripartum depression However, much research is needed to determine standardized protocol and evaluate effectiveness.
Advances in treatment for postpartum major depressive disorder
TLDR
Large, randomized, controlled trials of hormonal treatments in patients with PPD are warranted and treatment with mood stabilizers and/or antipsychotics in women with major depressive disorder, who meet the DSM-5 mixed features specifiers in the post-partum period, should be tested in controlled clinical trials.
Postpartum depression Part 2. Biological treatment: practical aspects & safety issues. Review of the literature
TLDR
Pharmacotherapy remains the most accessible method of treating depression in the puerperal period, however, knowledge about the safety of antidepressants during lactation is still insufficient.
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Repetitive Transcranial Magnetic Stimulation for the Acute Treatment of Major Depressive Episodes: A Systematic Review With Network Meta-analysis
TLDR
The estimated relative ranking of treatments suggested that priming low-frequency and bilateral rT MS might be the most efficacious and acceptable interventions among all rTMS strategies, and the design of larger RCTs investigating the potential of these approaches in the short-term treatment of MDD.
A review of the safety of repetitive transcranial magnetic stimulation as a clinical treatment for depression.
TLDR
There was a low incidence of accidental seizures and induced hypomania, both of which were associated with identified risk factors for which subjects should be screened, and supports its further development as a clinical treatment.
A systematic review and meta-analysis on the efficacy and acceptability of bilateral repetitive transcranial magnetic stimulation (rTMS) for treating major depression
TLDR
Bilateral rTMS is a promising treatment for MD as it provides clinically meaningful benefits that are comparable with those of standard antidepressants and unilateral rT MS, and it seems to be an acceptable treatment for depressed subjects.
Transcranial magnetic stimulation in the treatment of peripartum bipolar depression: a case report
TLDR
The case of a patient with bipolar II disorder who received rTMS for depression during the second and third trimesters of pregnancy, and the patient reported resolution of suicidal ideations, marked improvement is reported.
Response, remission and drop-out rates following high-frequency repetitive transcranial magnetic stimulation (rTMS) for treating major depression: a systematic review and meta-analysis of randomized, double-blind and sham-controlled trials
TLDR
HF-rTMS seems to be associated with clinically relevant antidepressant effects and with a benign tolerability profile, and is found equally effective as an augmentation strategy or as a monotherapy for MD, and when used in samples with primary unipolar MD or in mixed samples with unipolar and bipolar MD.
Transcranial magnetic stimulation for treatment of major depression during pregnancy: a review.
TLDR
The data available at this time support the efficacy and tolerability of rTMS for depression in pregnant women and there were no reports of damage/complications to unborn children.
Safety and feasibility of repetitive transcranial magnetic stimulation (rTMS) as a treatment for major depression during pregnancy
TLDR
A 28-year-old woman was diagnosed with major depression according to DSM-IV criteria for major depressive episode and agreed to receive repetitive transcranial magnetic stimulation (rTMS) rather than an antidepressant treatment, fearing that the medicine might affect the fetus.
Clinically Meaningful Efficacy and Acceptability of Low-Frequency Repetitive Transcranial Magnetic Stimulation (rTMS) for Treating Primary Major Depression: A Meta-Analysis of Randomized, Double-Blind and Sham-Controlled Trials
TLDR
LF-rTMS is a promising treatment for MD, as it provides clinically meaningful benefits that are comparable to those of standard antidepressants and high-frequency rTMS.
Transcranial magnetic stimulation during pregnancy
TLDR
High-frequency repetitive transcranial magnetic stimulation was well tolerated and found to be statistically and clinically effective in pregnant patients with treatment-resistant depression and contributed to the existing evidence of the antidepressant effect of rTMS in the treatment of depression in pregnancy.
An open label pilot study of transcranial magnetic stimulation for pregnant women with major depressive disorder.
TLDR
TMS appears to be a promising treatment option for pregnant women who do not wish to take antidepressant medications, and seven of ten subjects responded to treatment with transcranial magnetic stimulation.
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