A systematic review of the evidence on the treatment of rapid cycling bipolar disorder

@article{Fountoulakis2013ASR,
  title={A systematic review of the evidence on the treatment of rapid cycling bipolar disorder},
  author={K. Fountoulakis and D. Kontis and X. Gonda and L. Yatham},
  journal={Bipolar Disorders},
  year={2013},
  volume={15}
}
Fountoulakis KN, Kontis D, Gonda X, Yatham LN. A systematic review of the evidence on the treatment of rapid cycling bipolar disorder. 
Bipolar Disord 2013: 15: 115–137. © 2013 John Wiley & Sons A/S.Published by Blackwell Publishing Ltd. 
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References

SHOWING 1-10 OF 54 REFERENCES
Rapid‐cycling bipolar disorder: effects of long‐term treatments
TLDR
To compare responses to long‐term treatment of rapid‐cycling (RC) vs. non‐RC bipolar disorder patients and assess relative effectiveness of specific agents in RC patients, a large number of patients with bipolar disorder have received rapid cycling treatment. Expand
The efficacy of atypical antipsychotics in bipolar disorders.
  • R. Hirschfeld
  • Medicine, Psychology
  • The Journal of clinical psychiatry
  • 2003
TLDR
Atypical antipsychotic medications, used as monotherapy or as adjunctive therapy with mood stabilizers, have shown efficacy as well as well-tolerated side effect profiles, thus becoming valuable new resources in the treatment of bipolar disorder. Expand
The prospective course of rapid-cycling bipolar disorder: findings from the STEP-BD.
TLDR
While DSM-IV rapid cycling was prospectively observed in only a small percentage of patients, the majority of these patients had continued recurrences at lower but clinically significant rates, suggesting that cycling is on a continuum and that prevention of recurrence may require early intervention and restricted use of antidepressants. Expand
Olanzapine in the acute treatment of bipolar I disorder with a history of rapid cycling.
TLDR
Olanzapine was effective in reducing symptoms of mania and well tolerated in patients with bipolar I disorder with a rapid-cycling course and a sizeable placebo effect was obtained, possibly masking optimal therapeutic effect. Expand
Treatment of Rapid-Cycling Bipolar Disorder
TLDR
In the absence of clear treatment guidelines, the use and sequencing of drugs in complex combination treatment remains exploratory, but should be individualized based on careful prospective mood charting by the patient. Expand
New data on the use of lithium, divalproate, and lamotrigine in rapid cycling bipolar disorder
TLDR
A review of two major studies in an attempt to update understanding of the current therapies available to treat rapid cycling patients indicates that lamotrigine has the potential to complement the spectrum of lithium and divalproate through its greater efficacy for depressive symptoms. Expand
Efficacy of Quetiapine Monotherapy in Rapid-Cycling Bipolar Disorder in Comparison With Sodium Valproate
TLDR
In this study, quetiapine was more effective than VPA on the number of depressive days and similar to VPA in the treatment of manic symptoms and orthostatic dysregulation, sedation, and weight gain. Expand
Rapid and non-rapid cycling bipolar disorder: a meta-analysis of clinical studies.
TLDR
Rapid cycling is slightly more prevalent in women and in patients with bipolar II subtype, and hypothyroidism may be associated with mood destabilization in vulnerable patients. Expand
Bipolar rapid cycling: focus on depression as its hallmark.
TLDR
Preliminary data suggest that the combination of lithium and divalproex sodium administered continuously over 6 months appears to result in marked acute and continuation antimanic efficacy in 85% of patients and marked antidepressant efficacy in 60%. Expand
A single blind comparison of lithium and lamotrigine for the treatment of bipolar II depression.
TLDR
Lamotrigine and lithium were effective monotherapy for BDII depression, with comparable response and remission rates, though patient history indicated long standing depression unlikely to be alleviated by time. Expand
...
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2
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4
5
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