A systematic review of the effects of antipsychotic drugs on brain volume.

@article{Moncrieff2010ASR,
  title={A systematic review of the effects of antipsychotic drugs on brain volume.},
  author={Joanna Moncrieff and J Leo},
  journal={Psychological medicine},
  year={2010},
  volume={40 9},
  pages={
          1409-22
        }
}
BACKGROUND People with schizophrenia are often found to have smaller brains and larger brain ventricles than normal, but the role of antipsychotic medication remains unclear. METHOD We conducted a systematic review of magnetic resonance imaging (MRI) studies. We included longitudinal studies of brain changes in patients taking antipsychotic drugs and we examined studies of antipsychotic-naive patients for comparison purposes. RESULTS Fourteen out of 26 longitudinal studies showed a decline… CONTINUE READING

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Neuroimaging of Schizophrenia and Other Primary Psychotic Disorders

Galderisi Silvana, DeLisi Lynn, Borgwardt Stefan
  • Springer International Publishing
  • 2019
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