A systematic review of sequencing and combinations of systemic therapy in metastatic renal cancer.

@article{Albiges2015ASR,
  title={A systematic review of sequencing and combinations of systemic therapy in metastatic renal cancer.},
  author={Laurence K Albiges and Toni K Choueiri and Bernard Escudier and Matthew David Galsky and Dan George and Fabian Hofmann and Thomas B. L. Lam and Robert J Motzer and Peter F. A. Mulders and Camillo Porta and Thomas B Powles and Cora N Sternberg and Axel Bex},
  journal={European urology},
  year={2015},
  volume={67 1},
  pages={100-110}
}
CONTEXT The introduction of novel molecular-targeted agents has revolutionised the management of patients with metastatic renal cell carcinoma (mRCC). However, uncertainties remain over sequential or simultaneous combination therapies. OBJECTIVE To systematically review relevant literature comparing the clinical effectiveness and harms of different sequencing and combinations of systemic targeted therapies for mRCC. EVIDENCE ACQUISITION Relevant databases (including Medline, Cochrane… CONTINUE READING
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