A systematic review of malignancy-associated hemophagocytic lymphohistiocytosis that needs more attentions

@inproceedings{Wang2017ASR,
  title={A systematic review of malignancy-associated hemophagocytic lymphohistiocytosis that needs more attentions},
  author={Hongluan Wang and Lixia Xiong and Weiping Tang and Ying Zhou and Fei Li},
  booktitle={Oncotarget},
  year={2017}
}
As an infrequent but potentially life-threatening hyperinflammatory syndrome, hemophagocytic lymphohistiocytosis (HLH) is clinically characterized with prolonged fever, hepatosplenomegaly, cytopenia, hypertriglyceridemia, hyperferritinemia and hemophagocytosis in bone marrow, liver, spleen or lymph nodes. Malignancy-associated HLH (M-HLH), one type of acquired HLH, usually presents variable overlaps of symptoms with other types of HLH, thus resulting in higher incidence of misdiagnosis and… CONTINUE READING
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