A systematic review of hydromorphone in acute and chronic pain.

@article{Quigley2003ASR,
  title={A systematic review of hydromorphone in acute and chronic pain.},
  author={Columba Quigley and Phil J Wiffen},
  journal={Journal of pain and symptom management},
  year={2003},
  volume={25 2},
  pages={169-78}
}
While morphine is historically the gold standard for the management of severe cancer pain, some patients either do not achieve adequate analgesia, or suffer intolerable side effects from this drug. For these patients, alternatives such as hydromorphone are recommended. This review explores the evidence for the efficacy of hydromorphone in the management of pain. A systematic search, from 1966 to 2000, of published and unpublished randomized trials that involved the administration of… CONTINUE READING