A systematic review of gut-immune-brain mechanisms in Autism Spectrum Disorder.

  title={A systematic review of gut-immune-brain mechanisms in Autism Spectrum Disorder.},
  author={Atiqah Azhari and Farouq Azizan and Gianluca Esposito},
  journal={Developmental psychobiology},
  volume={61 5},
Despite decades of research, the etiological origins of Autism Spectrum Disorder (ASD) remain elusive. Recently, the mechanisms of ASD have encompassed emerging theories involving the gastrointestinal, immune, and nervous systems. While each of these perspectives presents its own set of supporting evidence, the field requires an integration of these modular concepts and an overarching view of how these subsystems intersect. In this systematic review, we have synthesized relevant evidences from… 
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