A systematic review and meta-analysis of pre-clinical studies assessing the effect of nicotine on osseointegration.


Nicotine has been associated with vasoconstriction and an impaired cellular healing response. It is therefore likely that nicotine jeopardizes osseointegration. This systematic review and meta-analysis was performed to assess pre-clinical studies on the effect of nicotine on implant osseointegration. Databases were searched up to and including March 2016… (More)
DOI: 10.1016/j.ijom.2016.12.003


5 Figures and Tables