A systematic review and meta-analysis of randomized controlled trials investigating the effects of supplementation with Nigella sativa (black seed) on blood pressure

@article{Sahebkar2016ASR,
  title={A systematic review and meta-analysis of randomized controlled trials investigating the effects of supplementation with Nigella sativa (black seed) on blood pressure},
  author={Amirhossein Sahebkar and Davide Soranna and Xiaoqiu Liu and Costas Thomopoulos and Luis E. Simental-Mend{\'i}a and Giuseppe Derosa and Pamela Maffioli and Gianfranco Parati},
  journal={Journal of Hypertension},
  year={2016},
  volume={34},
  pages={2127–2135}
}
Several reports suggest a beneficial effect of Nigella sativa on cardiometabolic risk factors, including blood pressure (BP). However, the magnitude of the BP-lowering effect of N. sativa remains controversial. We aimed to calculate this effect size of N. sativa through a systematic review and meta-analysis of randomized controlled trials (RCTs). PubMed, Cochrane Collaboration Library, and SCOPUS were used as data sources of RCTs published before 30 August 2015 (in English only) comparing N… Expand
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Favorable impact of powdered N. sativa (Kalonji) seed in capsule was noted on almost all variables, but results were not statistically significant and a larger study with adequate sample size is recommended. Expand
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Oral daily administration of 5 mL N. sativa oil to healthy volunteers for 8 weeks lowers systolic and diastolic BPs without any adverse effects, and results showed that in N. sitiva oil treated group the systols and diastsols decreased significantly compared with baseline and placebo group at the endpoint. Expand
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INDIGENOUS HERBAL PRODUCT NIGELLA SATIVA PROVED EFFECTIVE AS AN ANTIHYPERTENSIVE IN METABOLIC SYNDROME
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Nigella sativa oil was found to be effective antihypertensive agent in patients of metabolic syndrome and showed significant improvement with reference to SBP, DBP & LDL-cholesterol. Expand
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