A systematic review and meta‐analysis of the long‐term overall outcome of autism spectrum disorders in adolescence and adulthood

  title={A systematic review and meta‐analysis of the long‐term overall outcome of autism spectrum disorders in adolescence and adulthood},
  author={Hans Christoph Steinhausen and Christina Mohr Jensen and Marlene Briciet Lauritsen},
  journal={Acta Psychiatrica Scandinavica},
A systematic review and meta‐analysis of studies reporting on the overall outcome in terms of a global measure of adjustment in children with autistic disorders followed up in adolescence and adulthood. 
Old Age in Adults with ASD: Psychosocial Aspects—a Systematic Review
The present article is a systematic review of literature, examining the extent to which there is interest in old age of people with autistic spectrum disorders (ASD) and the issues in this field that
The long-term outcomes of a cohort of adolescents and adults from Greece with autism spectrum disorder
Overall outcomes in the Greek sample were consistent with international studies, and it seems that important contributing factors are comorbidity and especially overall lower cognitive function (intellectual disability), but further research is needed as well as enhanced adult-oriented research and intervention programs.
Description of a Danish Nationwide Survey of Adolescents and Adults Diagnosed With Autism Spectrum Disorders in Childhood: The AutCome Study
The study population was found to be representative of individuals diagnosed with ASD in childhood at Danish psychiatric hospitals, and lower rates of intellectual disability, psychiatric comorbidity, language difficulties, and epilepsy were found.
FARP‐1 deletion is associated with lack of response to autism treatment by early start denver model in a multiplex family
Children with autism spectrum disorder (ASD) display impressive clinical heterogeneity, also involving treatment response. Genetic variants can contribute to explain this large interindividual
Fifteen-Year Prospective Follow-Up Study of Adult Outcomes of Autism Spectrum Disorders Among Children Attending Centers in Five Regional Departments in France: The EpiTED Cohort
The results underscore the need for development of services and supports for adults with ASD in France who may also have already lacked access to adequate interventions and support services.
The Microsegmentation of the Autism Spectrum : Economic and Research Implications for Scotland
Economic research on autism and implications for Scotland, including how the economic cost of autism can inform strategy and planning.
Cognitive, Language, and Behavioral Outcomes in Children With Autism Spectrum Disorders Exposed to Early Comprehensive Treatment Models: A Meta-Analysis and Meta-Regression
Overall, most children with ASD who had ever participated in an early CTM made gains in many areas of functioning, especially in terms of symptom- and language-related outcomes, and meta-regression suggested that interventions with parent involvement, higher intensity, and longer treatment hours yielded greater improvements in IQ and social adaptive functioning, respectively.
Patterns of Continuity and Change in the Psychosocial Outcomes of Young Autistic People: a Mixed-Methods Study
There was far less variability in young people’s everyday functioning, with marked declines over the same period, but there was no straightforward one-to-one mapping between self-reported experiences of being autistic and standard measures of severity.
Autism spectrum disorder: outcomes in adulthood
The very variable findings reported in this review reflect the problems of conducting research into lifetime outcomes for individuals with a condition as heterogeneous as ASD.


Outcome and prognostic factors in infantile autism and similar conditions: A population-based study of 46 cases followed through puberty
IQ at diagnosis and communicative speech development before 6 years were the most important prognostic factors, but other trends were seen that also compare favorably with previous studies and some previously unreported trends also emerged.
Outcomes in adults with autism spectrum disorders: a historical perspective
The ways in which researchers have defined successful adult outcomes for individuals with autism spectrum disorders (ASDs) from the first systematic follow-up reports to the present day are examined.
A systematic review of the long-term outcome of early onset schizophrenia
The early manifestation of schizophrenia in childhood and adolescence still carries a particularly poor prognosis, and longer follow-up periods, male sex, and patients having been diagnosed before 1970 contribute predominantly to the rather poor course of EOS.
Asperger Syndrome and Autism: A Comparative Longitudinal Follow-Up Study More than 5 Years after Original Diagnosis
Males with Asperger syndrome had worse outcomes than expected given normal to high IQ, however, outcome was considerably better than for the comparison group of individuals with autism.
The outcome in children with childhood autism and Asperger syndrome originally diagnosed as psychotic. A 30-year follow-up study of subjects hospitalized as children
In adulthood the autistic patients had a poorer outcome than children with Asperger syndrome as regards education, employment, autonomy, marriage, reproduction and the need for continuing medical and institutional care.
Autism after Adolescence: Population-based 13- to 22-year Follow-up Study of 120 Individuals with Autism Diagnosed in Childhood
Children with autism as diagnosed in the 1960s, 1970s, and 1980s may have an even worse psychosocial outcome than previously believed.
Adults with Autism Spectrum Disorders
  • P. Howlin, P. Moss
  • Psychology
    Canadian journal of psychiatry. Revue canadienne de psychiatrie
  • 2012
The findings indicate that, as adults, many people with ASD, including those of normal IQ, are significantly disadvantaged regarding employment, social relationships, physical and mental health, and quality of life.