A systematic genetic polymorphism analysis of the CYP2C9 gene in four different geographical Han populations in mainland China.

@article{Xiong2011ASG,
  title={A systematic genetic polymorphism analysis of the CYP2C9 gene in four different geographical Han populations in mainland China.},
  author={Yuyu Xiong and M Wang and Ke Fang and Qinghe Xing and Guoyin Feng and Lu Shen and Liangsheng He and Shengying Qin},
  journal={Genomics},
  year={2011},
  volume={97 5},
  pages={277-81}
}
While many studies have been focused on CYP2C9*2 and *3 there was a lack of large full gene sequencing on CYP2C9, and this study was designed to fill this gap. We used direct sequencing to systematically screen genetic polymorphisms of the CYP2C9 gene including the 5' -flanking region (2kb), all exons and their adjoining intron regions and the 3' UTR in 400 unrelated healthy Chinese Han volunteers. A total of 27 different CYP2C9 polymorphisms were identified, 3 of which were novel, including… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 14 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 35 references

Genetic polymorphisms of cytochrome P450 enzymes 2 C9 and 2 C19 in a healthy iranian population

  • N. Zand
  • Clinical and Experimental Pharmacology…
  • 2007
3 Excerpts

Horsmans, CYP2C9, CYP2C19, ABCB1 (MDR1) genetic polymorphisms and phenytoin metabolism in a Black Beninese population, Pharmacogenetics and Genomics

  • A. Allabi, Y. J. Gala
  • 2005
1 Excerpt

Similar Papers

Loading similar papers…