A systematic analysis of the association studies between CASP8 D302H polymorphisms and breast cancer risk

@article{Zhang2017ASA,
  title={A systematic analysis of the association studies between CASP8 D302H polymorphisms and breast cancer risk},
  author={Yinliang Zhang and Wei Li and Yi Hong and Guoying Wu and Kan He and Dahai Liu},
  journal={Journal of Genetics},
  year={2017},
  volume={96},
  pages={283-289}
}
Caspase 8 (CASP8) is a regulator of apoptosis, whose genetic variation has been reported to be associated with the risk of various cancers. Especially, the single-nucleotide polymorphism (SNP) rs1045485, which generates the substitution D302H in CASP8, is likely to be associated with breast cancer. Several previous studies have reported the association of CASP8 D302H polymorphism with breast cancer; however, the results are inconsistent. To validate the association between CASP8 D302H… CONTINUE READING

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