A system to efficiently maintain embryonic lethal mutations in the flour beetle Tribolium castaneum

@article{Berghammer1999AST,
  title={A system to efficiently maintain embryonic lethal mutations in the flour beetle Tribolium castaneum},
  author={Andreas J Berghammer and Gregor Bucher and Florian Maderspacher and Martin Klingler},
  journal={Development Genes and Evolution},
  year={1999},
  volume={209},
  pages={382-389}
}
 Due to its small size, short life cycle, and easy maintenance, the flour beetle Tribolium castaneum is well suited for the genetic analysis of development. One drawback of Tribolium as a genetic system is, however, the difficulty of keeping embryonic lethal lines. Presently, only few lethal mutations can be kept as balanced stocks. Therefore, heterozygous carriers must be identified anew in every generation in order to maintain a recessive embryonic mutation. To alleviate this problem we have… CONTINUE READING

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