A synthetic homing endonuclease-based gene drive system in the human malaria mosquito

Abstract

Genetic methods of manipulating or eradicating disease vector populations have long been discussed as an attractive alternative to existing control measures because of their potential advantages in terms of effectiveness and species specificity. The development of genetically engineered malaria-resistant mosquitoes has shown, as a proof of principle, the… (More)
DOI: 10.1038/nature09937

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