A synthetic biochemistry module for production of bio-based chemicals from glucose.

@article{Opgenorth2016ASB,
  title={A synthetic biochemistry module for production of bio-based chemicals from glucose.},
  author={Paul H. Opgenorth and Tyler Paz Korman and James U. Bowie},
  journal={Nature chemical biology},
  year={2016},
  volume={12 6},
  pages={393-5}
}
Synthetic biochemistry, the cell-free production of biologically based chemicals, is a potentially high-yield, flexible alternative to in vivo metabolic engineering. To limit costs, cell-free systems must be designed to operate continuously with minimal addition of feedstock chemicals. We describe a robust, efficient synthetic glucose breakdown pathway and implement it for the production of bioplastic. The system's performance suggests that synthetic biochemistry has the potential to become a… CONTINUE READING
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