A syndrome of peripheral lipodystrophy, hyperlipidaemia and insulin resistance in patients receiving HIV protease inhibitors.

@article{Carr1998ASO,
  title={A syndrome of peripheral lipodystrophy, hyperlipidaemia and insulin resistance in patients receiving HIV protease inhibitors.},
  author={Andrew Carr and Katherine Samaras and Susan Burton and Matthew V. Law and Judith Freund and Donald J. Chisholm and David A. Cooper},
  journal={AIDS},
  year={1998},
  volume={12 7},
  pages={F51-8}
}
OBJECTIVE To describe a syndrome of peripheral lipodystrophy (fat wasting of the face, limbs and upper trunk), hyperlipidaemia and insulin resistance in patients receiving potent HIV protease inhibitor therapy. DESIGN Cross-sectional study. SETTING Outpatient clinic of a university teaching hospital. PATIENTS HIV-infected patients either receiving at least one protease inhibitor (n=116) or protease inhibitor-naive (n=32), and healthy men (n=47). INTERVENTIONS AND MAIN OUTCOME MEASURES… CONTINUE READING
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