A synaptic model of memory: long-term potentiation in the hippocampus

@article{Bliss1993ASM,
  title={A synaptic model of memory: long-term potentiation in the hippocampus},
  author={Tim V. P. Bliss and Graham L. Collingridge},
  journal={Nature},
  year={1993},
  volume={361},
  pages={31-39}
}
Long-term potentiation of synaptic transmission in the hippocampus is the primary experimental model for investigating the synaptic basis of learning and memory in vertebrates. The best understood form of long-term potentiation is induced by the activation of the N-methyl-d-aspartate receptor complex. This subtype of glutamate receptor endows long-term potentiation with Hebbian characteristics, and allows electrical events at the postsynaptic membrane to be transduced into chemical signals… Expand

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