A switch towards Th2 during serological rebound in children with congenital toxoplasmosis.

@article{Kahi1999AST,
  title={A switch towards Th2 during serological rebound in children with congenital toxoplasmosis.},
  author={Sandrine Kahi and Gr{\'e}goire Jacques No{\"e}l Cozon and Jean Michel Pinon and Timothy Greenland and Martine Wallon and Mounzer Al Kurdi and Josette Ferrandiz and François Peyron},
  journal={Clinical and experimental immunology},
  year={1999},
  volume={117 3},
  pages={524-8}
}
Serological rebounds occur frequently in patients with congenital toxoplasmosis, but remain poorly understood. A link between Th1 and Th2 cytokines and the pathophysiology of infectious diseases has been reported. Production of interferon-gamma (IFN-gamma) and IL-4 in supernatants of whole blood after in vitro specific Toxoplasma gondii stimulation and serum-specific IgE levels were studied in 31 congenitally infected children. IFN-gamma was produced at higher levels by lymphocytes from… CONTINUE READING