A switch in the mode of the sodium/calcium exchanger underlies an age-related increase in the slow afterhyperpolarization.

Abstract

During aging, the Ca(2+)-sensitive slow afterhyperpolarization (sAHP) of hippocampal neurons is known to increase in duration. This change has also been observed in the serotonergic cerebral giant cells (CGCs) of the pond snail Lymnaea stagnalis, but has yet to be characterized. In this article, we confirm that there is a reduction in firing rate, an… (More)
DOI: 10.1016/j.neurobiolaging.2015.06.012

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