A susceptibility gene for late‐onset idiopathic Parkinson's disease

  title={A susceptibility gene for late‐onset idiopathic Parkinson's disease},
  author={A. Hicks and H. P{\'e}tursson and T. J{\'o}nsson and H. Stef{\'a}nsson and H. J{\'o}hannsd{\'o}ttir and J. Sainz and M. Frigge and A. Kong and J. Gulcher and K. Stef{\'a}nsson and S. Sveinbj{\"o}rnsd{\'o}ttir},
  journal={Annals of Neurology},
  • A. Hicks, H. Pétursson, +8 authors S. Sveinbjörnsdóttir
  • Published 2002
  • Medicine
  • Annals of Neurology
  • Eight regions of the genome (PARK1‐8) have been implicated in autosomal dominant and autosomal recessive forms of early‐onset Parkinson's disease. These forms constitute a few of all cases. However, except for a haplotype in six families (PARK3), no study has successfully mapped a gene or described mutations that contribute to the common late‐onset Parkinson's disease. Some have even suggested that a genetic component does not exist. We cross‐matched our nationwide genealogy database with a… CONTINUE READING
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