A survey of therapy for advanced renal cell carcinoma.

  title={A survey of therapy for advanced renal cell carcinoma.},
  author={Michele Basso and Alessandra Cassano and Carlo Barone},
  journal={Urologic oncology},
  volume={28 2},
Renal cell carcinoma (RCC) is very resistant to both chemotherapy and radiotherapy. Localized disease can be cured by surgery but most patients are diagnosed when distant metastases are already present and about 30% of patients relapse after nephrectomy. Until 2 years ago, cytokine-based immunotherapy (interleukin-2 and interferon-alpha) was the only therapeutic option for advanced RCC patients. Fewer than 20% of patients benefit from this treatment, but some of these may experience very… CONTINUE READING


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