A survey of the syntheses of active pharmaceutical ingredients for antiretroviral drug combinations critical to access in emerging nations.

@article{Pinheiro2008ASO,
  title={A survey of the syntheses of active pharmaceutical ingredients for antiretroviral drug combinations critical to access in emerging nations.},
  author={Eloan dos Santos Pinheiro and Oct{\'a}vio Augusto Ceva Antunes and Joseph Fortunak},
  journal={Antiviral research},
  year={2008},
  volume={79 3},
  pages={143-65}
}
It has been roughly 25 years since the threat posed by human immunodeficiency virus type 1 (HIV-1) became widely known. The cumulative death toll from HIV/AIDS is now greater than 25 million. There are approximately 33 million people living worldwide with this disease, of whom about 68% (22.5 million) live in sub-Saharan Africa (http://www.avert.org/worldstats.htm). A number of antiretroviral (ARV) drugs have been approved for treatment of HIV/AIDS. Inhibitors of HIV reverse transcriptase (RTIs… CONTINUE READING