A surrogate-based approach for post-genomic partner identification

  title={A surrogate-based approach for post-genomic partner identification},
  author={Renuka C Pillutla and Ku-chuan Hsiao and Renee E Brissette and Paul S. Eder and Tony Giordano and Paul W Fletcher and Michael Lennick and Arthur J Blume and Neil I Goldstein},
  journal={BMC Biotechnology},
  pages={6 - 6}
BACKGROUND Modern drug discovery is concerned with identification and validation of novel protein targets from among the 30,000 genes or more postulated to be present in the human genome. While protein-protein interactions may be central to many disease indications, it has been difficult to identify new chemical entities capable of regulating these… CONTINUE READING