A surface antigen expressed by a subset of neurons in the vertebrate central nervous system.

@article{Hockfield1983ASA,
  title={A surface antigen expressed by a subset of neurons in the vertebrate central nervous system.},
  author={Susan Hockfield and R D G Mckay},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={1983},
  volume={80 18},
  pages={5758-61}
}
Many hypotheses for the specificity of connections in the nervous system postulate the presence of surface chemical differences between neurons. Hybridoma technology offers a potential route to identify such surface antigenic differences between neurons. Monoclonal antibody Cat-301 was one of a panel of antibodies generated by immunizing mice with homogenized adult cat spinal cord. At the light microscopic level, Cat-301 recognizes a subset of neurons in many areas of the vertebrate central… CONTINUE READING

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