A superoxide dismutase C mutant of Haemophilus ducreyi is virulent in human volunteers.

Abstract

Haemophilus ducreyi produces a periplasmic copper-zinc superoxide dismutase (Cu-Zn SOD), which is thought to protect the organism from exogenous reactive oxygen species generated by neutrophils during an inflammatory response. We had previously identified the gene, sodC, responsible for the production and secretion of Cu-Zn SOD and constructed an isogenic H… (More)

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@article{Bong2002ASD, title={A superoxide dismutase C mutant of Haemophilus ducreyi is virulent in human volunteers.}, author={Cliffton T H Bong and Kate R. Fortney and Barry Katz and Antoinette Foote Hood and Lani R San Mateo and Thomas H Kawula and Stanley M. Spinola}, journal={Infection and immunity}, year={2002}, volume={70 3}, pages={1367-71} }