A successful model to assess embryo development after transplantation of prophase nuclei.

@article{Takeuchi2004ASM,
  title={A successful model to assess embryo development after transplantation of prophase nuclei.},
  author={Takumi Takeuchi and Zev Rosenwaks and Gianpiero D. Palermo},
  journal={Human reproduction},
  year={2004},
  volume={19 4},
  pages={975-81}
}
BACKGROUND Germinal vesicle transplantation (GVT) provides a means of investigating interactions between karyoplasts and cytoplasts isolated from different cells. Technically, GVT can be accomplished with a high degree of efficiency without compromising the maturation of either the human or mouse oocyte nucleus. Although maturation, fertilization and preimplantation development have been established using GVT, full-term development has been reported only after supplementation with fresh mature… CONTINUE READING
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Full-term development of oocytes with dysfunctional ooplasm, after rescue by germinal vesicle transplantation

  • T Takeuchi, Z Rosenwaks, GD Palermo
  • Hum Reprod
  • 2003
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