A substantial number of Rasmussen syndrome patients have increased IgG, CD4+ T cells, TNFalpha, and Granzyme B in CSF.

@article{Takahashi2009ASN,
  title={A substantial number of Rasmussen syndrome patients have increased IgG, CD4+ T cells, TNFalpha, and Granzyme B in CSF.},
  author={Yukitoshi Takahashi and Jyun Mine and Yuko Kubota and Etsuko Yamazaki and Tateki Fujiwara},
  journal={Epilepsia},
  year={2009},
  volume={50 6},
  pages={1419-31}
}
PURPOSE We studied the immunologic molecules in cerebrospinal fluid (CSF) and discussed their evolutional changes in pediatric patients with Rasmussen syndrome (RS). METHODS CSF samples collected from 27 patients with RS (average onset age, 7.5 +/- 5.6 years) were studied. Cell count, protein, glucose, albumin, chloride, and immunoglobulin G (IgG) levels were measured by conventional methods. Surface markers of lymphocytes in CSF were examined by a cell sorter. Granzyme B, interferon gamma… CONTINUE READING