A subset of centrosomal proteins are arranged in a tubular conformation that is reproduced during centrosome duplication.

@article{Ou2000ASO,
  title={A subset of centrosomal proteins are arranged in a tubular conformation that is reproduced during centrosome duplication.},
  author={Young Y Ou and Jerome B. Rattner},
  journal={Cell motility and the cytoskeleton},
  year={2000},
  volume={47 1},
  pages={13-24}
}
The centrosome plays a fundamental role in organizing the interphase cytoskeleton and the mitotic spindle, and its protein complexity is modulated to support these functions. The centrosome must also duplicate itself once during each cell cycle, thus ensuring the formation of a bipolar spindle and its continuity through successive cell divisions. In this study, we have used a battery of antibodies directed against centrosomal components to study the general organization of the centrosome during… CONTINUE READING
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