A subpopulation of neurochemically-identified ventral tegmental area dopamine neurons is excited by intravenous cocaine.

@article{MejiasAponte2015ASO,
  title={A subpopulation of neurochemically-identified ventral tegmental area dopamine neurons is excited by intravenous cocaine.},
  author={Carlos A Mejias-Aponte and Changquan Ye and Antonello Bonci Bonci and Eugene A Kiyatkin and Marisela Morales},
  journal={The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year={2015},
  volume={35 5},
  pages={1965-78}
}
Systemic administration of cocaine is thought to decrease the firing rates of ventral tegmental area (VTA) dopamine (DA) neurons. However, this view is based on categorizations of recorded neurons as DA neurons using preselected electrophysiological characteristics lacking neurochemical confirmation. Without applying cellular preselection, we recorded the impulse activity of VTA neurons in response to cocaine administration in anesthetized adult rats. The phenotype of recorded neurons was… CONTINUE READING