A submaximal dose of insulin promotes net skeletal muscle protein synthesis in patients with severe burns.

@article{Ferrando1999ASD,
  title={A submaximal dose of insulin promotes net skeletal muscle protein synthesis in patients with severe burns.},
  author={Arny A. Ferrando and David L. Chinkes and Steven E. Wolf and Sara Matin and David N . Herndon and Robert R. Wolfe},
  journal={Annals of surgery},
  year={1999},
  volume={229 1},
  pages={11-8}
}
OBJECTIVE To investigate the hypothesis that a submaximal insulin dose reverses the net muscle catabolism associated with severe burns, and to determine its effects on amino acid kinetics. SUMMARY BACKGROUND DATA The authors previously showed that a maximal dose of insulin administered to patients with severe burns promoted skeletal muscle glucose uptake and net protein synthesis. However, this treatment was associated with caloric overload resulting from the large quantities of exogenous… CONTINUE READING
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