• Corpus ID: 238408333

A study protocol for a comparative effectiveness evaluation of antiandrogenic medications against Standard of Care

@inproceedings{Joneus2021ASP,
  title={A study protocol for a comparative effectiveness evaluation of antiandrogenic medications against Standard of Care},
  author={Paulina Jon'eus and Per Johansson and Sophie Langenskiold},
  year={2021}
}
This paper presents a study protocol for an effectiveness evaluation of antiandrogenic (NAM) medications (i.e. abiraterone acetate and enzalutamide) against standard of care in patients suffering from metastatic castrate resistant prostate cancer. The study protocol takes stock in the Rubin Causal Model for observational data in using historical comparisons for the analysis on three outcomes: mortality, pain and skeleton related events. We restrict the evaluation to 1,285 NAM patients with a… 

References

SHOWING 1-10 OF 14 REFERENCES

Study protocol for a comparative effectiveness evaluation of abiraterone acetate against enzalutamide: a longitudinal study based on Swedish administrative registers

A study protocol for a comparative effectiveness evaluation of abiraterone acetate against enzalutamide in clinical practice, two cancer drugs given to patients suffering from advanced prostate cancer is presented.

Epidemiology of prostate cancer

The literature on modifiable risk factors has continued to expand rapidly, and diet and lifestyle risk factors—focusing in particular on exercise and smoking cessation—as important determinants of both prostate cancer specific and overall health outcomes are reviewed.

Blinding and the Non-interference Assumption in Medical and Social Trials

This paper discusses the so-called non-interference assumption (NIA) grounding causal inference in trials in both medicine and the social sciences. It states that for each participant in the

Entropy Balancing for Causal Effects: A Multivariate Reweighting Method to Produce Balanced Samples in Observational Studies

Entropy balancing, a data preprocessing method to achieve covariate balance in observational studies with binary treatments, obviates the need for continual balance checking and iterative searching over propensity score models that may stochastically balance the covariate moments.

Statistics and Causal Inference

Abstract Problems involving causal inference have dogged at the heels of statistics since its earliest days. Correlation does not imply causation, and yet causal conclusions drawn from a carefully

AIDS: bioethics and public policy.

(2003). AIDS: Bioethics and public policy. New Review of Bioethics: Vol. 1, No. 1, pp. 127-144.

The behavior of maximum likelihood estimates under nonstandard conditions

This paper proves consistency and asymptotic normality of maximum likelihood (ML) estimators under weaker conditions than usual. In particular, (i) it is not assumed that the true distribution

A study protocol for a compara

  • Journal of Economic Literature
  • 2021

‘ Recent developments in the econometrics of program evaluation

  • Journal of Economic Literature
  • 2009

Using Least Squares to Approximate Unknown Regression Functions