A study on the investigation of cadmium chloride genotoxicity in rat bone marrow using micronucleus test and chromosome aberration analysis.

Abstract

In this study, we investigated the genotoxic and cytotoxic potential of cadmium chloride (CdCl2) in Wistar rat tibia bone marrow cells, using the structural chromosomal aberration (SCA) and micronucleus (MN) test systems. CdCl2 was administered to adult female rats as repeated i.p. doses of 0.5 mg/kg b.w. for 18 week (four months) at 48 h intervals… (More)

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