A study of var gene transcription in vitro using universal var gene primers.

@article{Taylor2000ASO,
  title={A study of var gene transcription in vitro using universal var gene primers.},
  author={Helen M.C. Taylor and Sue A Kyes and David Harris and Neline Kriek and Chris I Newbold},
  journal={Molecular and biochemical parasitology},
  year={2000},
  volume={105 1},
  pages={13-23}
}
The polymorphic multigene family, var, encodes the variant antigen, Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1), present on the surface of erythrocytes infected with the human malaria parasite, P. falciparum. PfEMP1 has been implicated in the pathology of malaria through its ability to bind to host endothelial receptors and uninfected erythrocytes. Understanding the relationship between host pathology, immune response and parasite variation is crucial, but requires a method of… CONTINUE READING

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Title A subset of group A-like var genes encodes the malaria parasite ligands for binding to human brain endothelial cells

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