A study of the mechanisms involved in the pulmonary arterial pressor response to hypoxia.

@article{Bergofsky1967ASO,
  title={A study of the mechanisms involved in the pulmonary arterial pressor response to hypoxia.},
  author={Edward H. Bergofsky and Stephen R Holtzman},
  journal={Circulation research},
  year={1967},
  volume={20 5},
  pages={
          506-19
        }
}
The mechanisms underlying the pulmonary arterial pressor response to hypoxia have been investigated by studying specimens of pulmonary and systemic vascular smooth muscle and the isolated pulmonary and systemic circulations. Hypoxia caused a unique and reversible loss of potassium and gain in sodium by pulmonary arterial smooth muscle that did not occur in pulmonary veins or systemic arteries. These changes in electrolyte concentrations were calculated by the Nernst equation to be associated… CONTINUE READING

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Effects of ouabain, low K+, and aldosterone on hypoxic pressor reactivity of rat lungs.

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