A study of the liver of goats immunized with a synthetic peptide of the Sm14 antigen and challenged with Fasciola hepatica.

@article{Zafra2008ASO,
  title={A study of the liver of goats immunized with a synthetic peptide of the Sm14 antigen and challenged with Fasciola hepatica.},
  author={Rafael G{\'o}mez Zafra and Leandro Buffoni and Alvaro Mart{\'i}nez-Moreno and A Perez-Ecija and Francisco Javier Mart{\'i}nez-Moreno and Jos{\'e} P{\'e}rez},
  journal={Journal of comparative pathology},
  year={2008},
  volume={139 4},
  pages={169-76}
}
A synthetic peptide of the Sm14 antigen of Schistosoma mansoni was used to immunize goats against experimental challenge with Fasciola hepatica. The goats used consisted of: group 1 (unimmunized and uninfected [controls]); group 2 (unimmunized and infected); group 3 (immunized and infected). Compared with group 2, the animals of group 3 showed at necropsy a reduction in hepatic worm burden; however, because of variability in the two groups this reduction was not statistically significant. A… CONTINUE READING

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