A study of the factors affecting the emergence of the gametocytes of Plasmodium gallinaceum from the erythrocytes and the exflagellation of the male gametocytes

  title={A study of the factors affecting the emergence of the gametocytes of Plasmodium gallinaceum from the erythrocytes and the exflagellation of the male gametocytes},
  author={Ann Bishop and Elspeth W. McConnachie},
  pages={192 - 215}
1. The emergence of the gametocytes of Plasmodium gallinaceum from the erythrocytes and the exflagellation of the male gametocyte were inhibited completely when infected blood was exposed to an atmosphere of 5 % CO2 and 95 % O2, or 5 % CO2 and 95 % N2. When these gas mixtures were replaced by air, the gametocytes emerged from the erythrocytes and the male gametocytes exflagellated after approximately the same interval as they did in newly drawn blood exposed to air, or in blood ingested by… 

Further observations on the in vitro development of the gametocytes of Plasmodium gallinaceum

Within the range of inorganic salts tested, Na, HCO3 and C1 ions constituted the minimal requirement for the normal in vitro development of the male gametocytes.

Factors determining the in vitro emergence of sexual stages of Hepatozoon clamatae from erythrocytes of the Green Frog (Rana clamitans)

The results suggest that conditions necessary for emergence of sexual stages of bloodstream Apicomplexa from erythrocytes vary among genera.

The roles of temperature, pH and mosquito factors as triggers of male and female gametogenesis of Plasmodium berghei in vitro

The presence of additional Gametocyte Activating Factor (GAF) present in Anopheles stephensi tissue extracts is reported, which induce both male and female gametogenesis at the otherwise non-permissive pH of 7·3 in vitro but are unable to overcome the low temperature requirement.

Identification of xanthurenic acid as the putative inducer of malaria development in the mosquito

It is shown that low concentrations of xanthurenic acid can act together with pH to induce gametogenesis in vitro, and could form the basis of the rational development of new methods of interrupting the transmission of malaria using drugs or new refractory mosquito genotypes to block parasitegametogenesis.

Early Stages in the Differentiation of Gametocytes of Haemoproteus columbae Kruse

SYNOPSIS The sexes of mature gametocytes of Haemoproteus columbae Kruse circulating in the blood of the domestic pigeon can be identified in the electron microscope by the same criteria that

Plasmodium ookinete development in the mosquito midgut: a case of reciprocal manipulation

Study of ookinete development and of the cellular and biochemical complexities of the mosquito gut may lead to the design of novel strategies to block the transmission of malaria.

Sexual development of malarial parasites.

Determination of mosquito bloodmeal pH in situ by ion-selective microelectrode measurement: implications for the regulation of malarial gametogenesis

Xanthurenic acid is shown to extend the pH-range of exflagellation in vitro in a dose-dependent manner to values that are observed in the bloodmeal, suggesting that in vivo malarial gametogenesis could be further regulated by both these factors.

Electron microscope study of the blood stages of Plasmodium tropiduri, a lizard malaria parasite

The comparative study of the structure of the cytostomes of the merozoites and the trophozoites, and of their relationships with the membranes that limit the parasites, gives new evidence that the external membrane of the troPHozoites schizonts, and gametocytes is derived from the host cell.



The Goulstonian Lectures on the Life-History of the Malaria Germ Outside the Human Body

It is seen that so long as the future extra-corporeal form of the plasmodium is inside the human body it is enclosed in a blood corpuscle from which it emerges only as a passive body-a motionless passive spore, and it is impossible for the plAsmodium to escape from its host by its own efforts.

Observations on a Condition Necessary to the Transformation of the Malaria Crescent

  • R. Ross
  • Medicine
    British medical journal
  • 1897
It may be, however, that the mere pricking of the tense capsule of the gland, even by needle punctures, may serve to relieve tension and thereby pain, and the belief that subcutaneous incision of the glands may be attended with beneficial results is believed.

An investigation of the intracellular pH of crab muscle fibres by means of micro‐glass and micro‐tungsten electrodes

The intracellular pH of tissues, especially of muscle, is of interest for various reasons and changes in pH may be related to the way in which variations of external potassium concentration or of membrane potential influence metabolic activity.

A method for determining the pH of small quantities of fluid

The micro-glass electrode used in measuring the pH of blood from the stomachs of mosquitoes was a modification of that described by Caldwell (1954). The electrode was made of capillary tubing, drawn

Sulphanilamide as a Specific Inhibitor of Carbonic Anhydrase

This enzyme plays an important part in accelerating the carbon dioxide output in the lungs; it appears also to promote the formation of hydrochloric acid by the parietal cells of gastric mucosa.

An Outline of General Physiology

biographies give the reader a more intimate knowledge of the interests and research careers of each of the participants. Because the book is a running account of the provocative discussion of

Ueber den Einfluss physikalischer Reize auf die Bildung der Geschlectszellen bei Hamoproteus

  • Hyg. Rdsch. 13, 283.
  • 1903