A study of the dependence of the human erythrocyte glucose transport system on membrane sulfhydryl groups

@article{Smith1973ASO,
  title={A study of the dependence of the human erythrocyte glucose transport system on membrane sulfhydryl groups},
  author={R. P. Smith and George L. Ellman},
  journal={The Journal of Membrane Biology},
  year={1973},
  volume={12},
  pages={177-188}
}
SummaryA brief review of the data relating the glucose transport system and other membrane functions of red cells to surface sulfhydryl groups is presented. The effect of a variety of sulfhydryl reagents on glucose efflux rates from loaded red cells was studied. Neither iodoacetate nor iodoacetamide at 5mm inhibited efflux. Several maleimide derivatives and disulfides inhibited efflux in 0.7 to 2.0mm concentrations. Organomercury compounds, on the other hand, were active in the 0.07 to 0.1mm… CONTINUE READING

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