A study of the biologically active conformation of the cholecystokinin-4 dipeptide analogue GB-115

Abstract

The biologically active conformation of N-(6-phenylhexanoyl)glycyl-tryptophan amide (GB-115), a highly active cholecystokinin-4 retro dipeptide analogue with the anxiolytic activity, has been studied using the conformational analysis by 1H NMR spectroscopy in solution and the method of sterically restricted analogues. A study of the relationship between the… (More)
DOI: 10.1134/S1068162013030060

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